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TABLE OF CONTENTS

A.    Studies Employing 2N₃- and 8N₃-ATP Photoaffinity Analogs

B.    Studies Employing 8N₃cAMP Photoaffinity Analogs

C.    Studies Employing ATP-Azidoanilide and ATP-Benzophenone Photoaffinity Analogs

D.    Studies Employing 8N₃GTP and GTP-Azido Anilide Photoaffinity Analogs

E.    Studies Employing 5N₃UTP and 5N₃UDP Analogs

F.    Studies Employing Biotinylated Nucleotide Photoaffinity Analogs

A.    Studies Employing 2N₃- and 8N₃-ATP Photoaffinity Analogs

	ATP binding to the first nucleotide binding domain of multidrug resistance-associated protein plays a regulatory role at low nucleotide concentration, whereas ATP hydrolysis at the second plays a dominant role in ATP-dependent leukotriene C4 transport. Yang R, Cui L, Hou YX, Riordan JR, Chang XB. J Biol Chem. 2003 Aug 15;278(33):30764-71. Epub 2003 Jun 03. (12783859)
	Prolonged nonhydrolytic interaction of nucleotide with CFTR's NH2-terminal nucleotide binding domain and its role in channel gating. Basso C, Vergani P, Nairn AC, Gadsby DC. J Gen Physiol. 2003 Sep;122(3):333-48. (12939393)
	Functional interaction between the two halves of the photoreceptor-specific ATP binding cassette protein ABCR (ABCA4). Evidence for a non-exchangeable ADP in the first nucleotide binding domain. Ahn J, Beharry S, Molday LL, Molday RS. J Biol Chem. 2003 Jul 29. (12888572)
	Nucleotide interactions with membrane-bound transporter associated with antigen processing proteins. Lapinski PE, Raghuraman G, Raghavan M. J Biol Chem 2003 Mar 7;278(10):8229-37. (12501238)
	Effects of mutations of ABCA1 in the first extracellular domain on subcellular trafficking and ATP binding/hydrolysis. Tanaka AR, Abe-Dohmae S, Ohnishi T, Aoki R, Morinaga G, Okuhira K, Ikeda Y, Kano F, Matsuo M, Kioka N, Amachi T, Murata M, Yokoyama S, Ueda K. J Biol Chem 2003 Mar 7;278(10):8815-9. Erratum in: J Biol Chem. 2003 Apr 18;278(16):14586. (12509412)
	Application of vanadate-induced nucleotide trapping to plant cells for detection of ABC proteins. Terasaka K, Shitan N, Sato F, Maniwa F, Ueda K, Yazaki K. Plant Cell Physiol 2003 Feb;44(2):198-200. (12610223)
	Characterization of berberine transport into Coptis japonica cells and the involvement of ABC protein. Sakai K, Shitan N, Sato F, Ueda K, Yazaki K. J Exp Bot 2002 Sep;53(376):1879-86. (12177126)
	ATP binding/hydrolysis by and phosphorylation of peroxisomal ATP-binding cassette proteins PMP70 (ABCD3) and adrenoleukodystrophy protein (ABCD1). Tanaka AR, Tanabe K, Morita M, Kurisu M, Kasiwayama Y, Matsuo M, Kioka N, Amachi T, Imanaka T, Ueda K. J Biol Chem 2002 Oct 18;277(42):40142-7. (12176987)
	Functional characterization of the adrenoleukodystrophy protein (ALDP) and disease pathogenesis. Gartner J, Dehmel T, Klusmann A, Roerig P. Endocr Res 2002 Nov;28(4):741-8. (12530690)
	Heteromultimerization modulates P2X receptor functions through participating extracellular and C-terminal subdomains. Koshimizu TA, Ueno S, Tanoue A, Yanagihara N, Stojilkovic SS, Tsujimoto G. J Biol Chem 2002 Dec 6;277(49):46891-9. (12361958)
	Cooperative nucleotide binding to the human erythrocyte sugar transporter. Cloherty EK, Levine KB, Graybill C, Carruthers A. Biochemistry. 2002 Oct 22;41(42):12639-51. (12379106)
	Molecular determinants of sugar transport regulation by ATP.Levine KB, Cloherty EK, Hamill S, Carruthers A. Biochemistry. 2002 Oct 22;41(42):12629-38. (12379105)
	Functional analysis of the C-terminal boundary of the second nucleotide binding domain of the cystic fibrosis transmembrane conductance regulator and structural implications. Gentzsch M, Aleksandrov A, Aleksandrov L, Riordan JR. Biochem J 2002 Sep 1;366(Pt 2):541-8. (12020354)
	Mutations in the linker domain of NBD2 of SUR inhibit transduction but not nucleotide binding. Matsuo M, Dabrowski M, Ueda K, Ashcroft FM. EMBO J 2002 Aug 15;21(16):4250-8. (12169627)
	Nucleotide binding and nucleotide hydrolysis properties of the ABC transporter MRP6 (ABCC6). Cai J, Daoud R, Alqawi O, Georges E, Pelletier J, Gros P. Biochemistry 2002 Jun 25;41(25):8058-67. (12069597)
	Novel ATPase of SNF2-like protein family interacts with androgen receptor and modulates androgen-dependent transcription. Rouleau N, Domans'kyi A, Reeben M, Moilanen AM, Havas K, Kang Z, Owen-Hughes T, Palvimo JJ, Janne OA. Mol Biol Cell 2002 Jun;13(6):2106-19. (12058073)
	The First Nucleotide Binding Domain of Cystic Fibrosis Transmembrane Conductance Regulator Is a Site of Stable Nucleotide Interaction, whereas the Second Is a Site of Rapid Turnover. Aleksandrov L, Aleksandrov AA, Chang XB, Riordan JR. J Biol Chem 2002 May 3;277(18):15419-25. (11861646)
	Selected BTB/POZ-kelch proteins bind ATP. T'Jampens D, Devriendt L, De Corte V, Vandekerckhove J, Gettemans J. FEBS Lett 2002 Apr 10;516(1-3):20-6. (11959095)
	Characterization of the nucleotide-binding capacity and the ATPase activity of the PIP3-binding protein JFC1. Catz SD, Johnson JL, Babior BM. Proc Natl Acad Sci U S A 2001 Sep 25;98(20):11230-5. (11553774)
	Purification and characterization of acyl-acyl carrier protein synthetase from oleaginous yeast and its role in triacylglycerol biosynthesis. Gangar A, Karande AA, Rajasekharan R. Biochem J 2001 Dec 1;360(Pt 2):471-9. (11716776)
	Evidence for the vectorial nature of drug (substrate)-stimulated ATP hydrolysis by human P-glycoprotein. Sauna ZE, Smith MM, Muller M, Ambudkar SV. J Biol Chem 2001 Sep 7;276(36):33301-4. (11451943)
	The yeast a-factor transporter Ste6p, a member of the ABC superfamily, couples ATP hydrolysis to pheromone export. Ketchum CJ, Schmidt WK, Rajendrakumar GV, Michaelis S, Maloney PC. J Biol Chem 2001 Aug 3;276(31):29007-11. (11389139)
	Functional expression of multidrug resistance protein 1 in Pichia pastoris. Cai J, Daoud R, Georges E, Gros P. Biochemistry 2001 Jul 27;40(28):8307-16. (11444977)
	Functionally similar vanadate-induced 8-azidoadenosine 5'-[alpha-(32)P]Diphosphate-trapped transition state intermediates of human P-glycoprotin are generated in the absence and presence of ATP hydrolysis. Sauna ZE, Smith MM, Muller M, Ambudkar SV. J Biol Chem 2001 Jun 15;276(24):21199-208. (11287418)
	Modulation of multidrug resistance protein 1 (MRP1/ABCC1) transport and atpase activities by interaction with dietary flavonoids. Leslie EM, Mao Q, Oleschuk CJ, Deeley RG, Cole SP. Mol Pharmacol 2001 May;59(5):1171-80. (11306701)
	Cloning and characterization of the subunits comprising the catalytic core of the Trypanosoma brucei mitochondrial ATP synthase. Brown B SV, Stanislawski A, Perry QL, Williams N. Mol Biochem Parasitol 2001 Apr 6;113(2):289-301. (11295183)
	Differential interactions of nucleotides at the two nucleotide binding domains of the cystic fibrosis transmembrane conductance regulator. Aleksandrov L, Mengos A, Chang X, Aleksandrov A, Riordan JR. J Biol Chem 2001 Apr 20;276(16):12918-23. (11279083)
	Functional reassembly of ATP-dependent xenobiotic transport by the N- and C-terminal domains of RLIP76 and identification of ATP binding sequences. Awasthi S, Cheng JZ, Singhal SS, Pandya U, Sharma R, Singh SV, Zimniak P, Awasthi YC. Biochemistry 2001 Apr 3;40(13):4159-68. (11300797)
	Characterization of the catalytic cycle of ATP hydrolysis by human P-glycoprotein. The two ATP hydrolysis events in a single catalytic cycle are kinetically similar but affect different functional outcomes. Sauna ZE, Ambudkar SV. J Biol Chem 2001 Apr 13;276(15):11653-61. (11154703)
	Covalent modification of the non-catalytic sites of the H(+)-ATPase from chloroplasts with 2-azido-[alpha-(32)P]ATP and its effect on ATP synthesis and ATP hydrolysis. Possmayer FE, Hartog AF, Berden JA, Graber P. Biochim Biophys Acta 2001 Feb 9;1510(1-2):378-400. (11342174)
	Covalent modification of the catalytic sites of the H+-ATPase from chloroplasts and 2-nitreno-ADP. Modification of the catalytic site 1 (tight) and catalytic sites 1 and 2 together impairs both uni-site and multi-site catalysis of ATP synthesis and ATP hydrolysis. Possmayer FE, Hartog AF, Berden JA, Graber P. Biochim Biophys Acta. 2000 Jul 20; 1459(1): 202-17.  (10924912)
	Covalent modification of the catalytic sites of the H(+)-ATPase from chloroplasts with 2-nitreno-ADP. Modification of the catalytic site 1 (tight) and catalytic sites 1 and 2 together impairs both uni-site and multi-site catalysis of ATP synthesis and ATP hydrolysis. Possmayer FE, Hartog AF, Berden JA, Graber P. Biochim Biophys Acta. 2000 Jul 20; 1459(1): 202-217. (11004435)
	Covalent modification of the catalytic sites of the H(+)-ATPase from chloroplasts, CF(0)F(1), with 2-azido-[alpha-(32)P]ADP: modification of the catalytic site 2 (loose) and the catalytic site 3 (open) impairs multi-site, but not uni-site catalysis of both ATP synthesis and ATP hydrolysis. Possmayer FE, Hartog AF, Berden JA, Graber P. Biochim Biophys Acta. 2000 Jan 10; 1456(2-3): 77-98. (10627297)
	Mapping of the ATP-binding sites on inositol 1,4,5-trisphosphate receptor type 1 and type 3 homotetramers by controlled proteolysis and photoaffinity labeling. Maes K, Missiaen L, Parys JB, De Smet P, Sienaert I, Waelkens E, Callewaert G, De Smedt H. J Biol Chem 2001 Feb 2;276(5):3492-7. (11035010)
	Functional asymmetry of the two nucleotide binding domains in the ABC transporter Ste6. Proff C, Kolling R. Mol Gen Genet 2001 Feb;264(6):883-93. (11254136)
	Photoaffinity labeling and photoaffinity cross-linking of phosphofructokinase-1 from Saccharomyces cerevisiae by 8-azidoadeninenucleotides. Knoche M, Monnich K, Schafer HJ, Kopperschlager G. Arch Biochem Biophys 2001 Jan 15;385(2):301-10. (11368011)
	Functional analysis of a mutant sulfonylurea receptor, SUR1-R1420C, that is responsible for persistent hyperinsulinemic hypoglycemia of infancy. Matsuo M, Trapp S, Tanizawa Y, Kioka N, Amachi T, Oka Y, Ashcroft FM, Ueda K. J Biol Chem 2000 Dec 29;275(52):41184-91. (10993895)
	Nonequivalent nucleotide trapping in the two nucleotide binding folds of the human multidrug resistance protein MRP1. Nagata K, Nishitani M, Matsuo M, Kioka N, Amachi T, Ueda K. J Biol Chem 2000 Jun 9;275(23):17626-30. (10747957)
	Mutational analysis of conserved carboxylate residues in the nucleotide binding sites of P-glycoprotein. Urbatsch IL, Julien M, Carrier I, Rousseau ME, Cayrol R, Gros P. Biochemistry 2000 Nov 21;39(46):14138-49. (11087362)
	Cloning, characterization and tissue distribution of the rat ATP-binding cassette (ABC) transporter ABC2/ABCA2. Zhao LX, Zhou CJ, Tanaka A, Nakata M, Hirabayashi T, Amachi T, Shioda S, Ueda K, Inagaki N. Biochem J 2000 Sep 15;350 Pt 3:865-72. (10970803)
	Analysis of a nucleotide-binding site of 5-lipoxygenase by affinity labelling: binding characteristics and amino acid sequences. Zhang YY, Hammarberg T, Radmark O, Samuelsson B, Ng CF, Funk CD, Loscalzo J. Biochem J 2000 Nov 1;351 Pt 3:697-707. (11042125)
	Different binding properties and affinities for ATP and ADP among sulfonylurea receptor subtypes, SUR1, SUR2A, and SUR2B. Matsuo M, Tanabe K, Kioka N, Amachi T, Ueda K. J Biol Chem 2000 Sep 15;275(37):28757-63. (10893240)
	MDR3 P-glycoprotein, a phosphatidylcholine translocase, transports several cytotoxic drugs and directly interacts with drugs as judged by interference with nucleotide trapping. Smith AJ, van Helvoort A, van Meer G, Szabo K, Welker E, Szakacs G, Varadi A, Sarkadi B, Borst P. J Biol Chem 2000 Aug 4;275(31):23530-9. (10918072)
	Identification of ecto-PKC on surface of human platelets: role in maintenance of latent fibrinogen receptors. Babinska A, Hogan MV, Sobocki T, Sobocka MB, Ehrlich YH, Kornecki E. Am J Physiol Heart Circ Physiol 2000 Jun;278(6):H2008-19. (10843900)
	Covalent modification of the catalytic sites of the H(+)-ATPase from chloroplasts, CF(0)F(1), with 2-azido-[alpha-(32)P]ADP: modification of the catalytic site 2 (loose) and the catalytic site 3 (open) impairs multi-site, but not uni-site catalysis of both ATP synthesis and ATP hydrolysis. Possmayer FE, Hartog AF, Berden JA, Graber P. Biochim Biophys Acta 2000 Jan 10;1456(2-3):77-98. (10627297)
	Covalent modification of the catalytic sites of the H(+)-ATPase from chloroplasts with 2-nitreno-ADP. Modification of the catalytic site 1 (tight) and catalytic sites 1 and 2 together impairs both uni-site and multi-site catalysis of ATP synthesis and ATP hydrolysis. Possmayer FE, Hartog AF, Berden JA, Graber P. Biochim Biophys Acta 2000 Jul 20;1459(1):202-217. (11004435)
	Structural and functional features of the Escherichia coli F1-ATPase. Gruber G. J Bioenerg Biomembr 2000 Aug;32(4):341-6. (11768295)
	Allosteric interactions between the two non-equivalent nucleotide binding domains of multidrug resistance protein MRP1. Hou Y, Cui L, Riordan JR, Chang X. J Biol Chem 2000 Jul 7;275(27):20280-7. (10781583)
	The hydrophilic N-terminal domain complements the membrane-anchored C-terminal domain of the sensor kinase KdpD of Escherichia coli. Heermann R, Altendorf K, Jung K. J Biol Chem 2000 Jun 2;275(22):17080-5. (10747873)
	Differential modulation of inositol 1,4,5-trisphosphate receptor type 1 and type 3 by ATP. Maes K, Missiaen L, De Smet P, Vanlingen S, Callewaert G, Parys JB, De Smedt H. Cell Calcium 2000 May;27(5):257-67. (10859592)
	Covalent modification of the catalytic sites of the H+-ATPase from chloroplasts and 2-nitreno-ADP. Modification of the catalytic site 1 (tight) and catalytic sites 1 and 2 together impairs both uni-site and multi-site catalysis of ATP synthesis and ATP hydrolysis. Possmayer FE, Hartog AF, Berden JA, Graber P. Biochim Biophys Acta 2000 Jul 20;1459(1):202-17. (10924912)
	Direct photoaffinity labeling of Kir6.2 by [gamma-(32)P]ATP-[gamma]4-azidoanilide. Tanabe K, Tucker SJ, Ashcroft FM, Proks P, Kioka N, Amachi T, Ueda K. Biochem Biophys Res Commun 2000 Jun 7;272(2):316-9. (9933580)
	Analysis of the properties of the N-terminal nucleotide-binding domain of human P-glycoprotein. Booth CL, Pulaski L, Gottesman MM, Pastan I. Biochemistry 2000 May 9;39(18):5518-26. (10820025)
	Comparison of the functional characteristics of the nucleotide binding domains of multidrug resistance protein 1. Gao M, Cui HR, Loe DW, Grant CE, Almquist KC, Cole SP, Deeley RG. J Biol Chem 2000 Apr 28;275(17):13098-108. (10777615)
	Covalent modification of the catalytic sites of the H(+)-ATPase from chloroplasts, CF(0)F(1), with 2-azido-[alpha-(32)P]ADP: modification of the catalytic site 2 (loose) and the catalytic site 3 (open) impairs multi-site, but not uni-site catalysis of both ATP synthesis and ATP hydrolysis. Possmayer FE, Hartog AF, Berden JA, Graber P. Biochim Biophys Acta 2000 Jan 10;1456(2-3):77-98. (10627297)
	ATP binding properties of the nucleotide-binding folds of SUR1. Matsuo M, Kioka N, Amachi T, Ueda K. J Biol Chem 1999 Dec 24;274(52):37479-82. (10601323)
	Mapping of ATP binding regions in poly(A) polymerases by photoaffinity labeling and by mutational analysis identifies a domain conserved in many nucleotidyltransferases. Martin G, Jeno P, Keller W. Protein Sci 1999 Nov;8(11):2380-91. (10595540)
	Intrinsic nucleoside diphosphate kinase-like activity is a novel function of the 20 S proteasome. Yano M, Mori S, Kido H. J Biol Chem 1999 Nov 26;274(48):34375-82. (10567415)
	The role of lysine 185 in the kir6.2 subunit of the ATP-sensitive channel in channel inhibition by ATP. Reimann F, Ryder TJ, Tucker SJ, Ashcroft FM. J Physiol 1999 Nov 1;520 Pt 3:661-9. (10545134)
	Photoaffinity labeling of wild-type and mutant forms of the yeast V-ATPase A subunit by 2-azido-[(32)P]ADP. MacLeod KJ, Vasilyeva E, Merdek K, Vogel PD, Forgac M. J Biol Chem 1999 Nov 12;274(46):32869-74. (10551850)
	Both ATP sites of human P-glycoprotein are essential but not symmetric. Hrycyna CA, Ramachandra M, Germann UA, Cheng PW, Pastan I, Gottesman MM. Biochemistry 1999 Oct 19;38(42):13887-99. (10529234)
	Purification of the human apical conjugate export pump MRP2 reconstitution and functional characterization as substrate-stimulated ATPase. Hagmann W, Nies AT, Konig J, Frey M, Zentgraf H, Keppler D. Eur J Biochem 1999 Oct 1;265(1):281-9. (10491184)
	Metal-dependent nucleotide binding to the Escherichia coli rotamase SlyD. Mitterauer T, Nanoff C, Ahorn H, Freissmuth M, Hohenegger M. Biochem J 1999 Aug 15;342 ( Pt 1):33-9. (10432297)
	NEM modification prevents high-affinity ATP binding to the first nucleotide binding fold of the sulphonylurea receptor, SUR1. Michinori Matsuoa, Stephen J. Tucker, Frances M. Ashcroft, Teruo Amachi and Kazumitsu Ueda. FEBS LETTERS   1999, 458:3:292-294
	Direct photoaffinity labeling of the kir6.2 subunit of the ATP-sensitive K+ channel by 8-azido-ATP. Tanabe et al., (1999). J. Biol. Chem. 274:3931-3933. (9933580)
	One of the non-exchangeable nucleotides of the mitochondrial F1-ATPase is bound at a beta-subunit: evidence for a non-rotatory two-site catalytic mechanism Hartog AF, Berden JA. Biochim Biophys Acta 1999 Jun 30;1412(2):79-93. (10393252)
	ATP nucleotidylation of creatine kinase. David SS, Haley BE. Biochemistry 1999 Jun 29;38(26):8492-500. (10387096)
	Molecular aspects of fatty acid transport: mutations in the IYTSGTTGXPK motif impair fatty acid transport protein function. Stuhlsatz-Krouper SM, Bennett NE, Schaffer JE. Prostaglandins Leukot Essent Fatty Acids 1999 May-Jun;60(5-6):285-9. (10471110)
	Monoclonal antibodies that inhibit the transport function of the 190-kDa multidrug resistance protein, MRP. Localization of their epitopes to the nucleotide-binding domains of the protein. Hipfner DR, Mao Q, Qiu W, Leslie EM, Gao M, Deeley RG, Cole SP. J Biol Chem 1999 May 28;274(22):15420-6. (10336431)
	Nucleotide occlusion in the human cystic fibrosis transmembrane conductance regulator. Different patterns in the two nucleotide binding domains. Szabo K, Szakacs G, Hegeds T, Sarkadi B. J Biol Chem 1999 Apr 30;274(18):12209-12. (10212185)
	Cooperative binding of ATP and MgADP in the sulfonylurea receptor is modulated by glibenclamide. Ueda K, Komine J, Matsuo M, Seino S, Amachi T. Proc Natl Acad Sci U S A 1999 Feb 16;96(4):1268-72. (9990013)
	Developing a snapshot of the ATP binding domain(s) of aminoglycoside phosphotransferases. Perlin MH, Brown SA, Dholakia JN. Front Biosci 1999 Jan 1;4:D63-71. (9872732)
	Non-equivalent cooperation between the two nucleotide-binding folds of P-glycoprotein. Takada Y, Yamada K, Taguchi Y, Kino K, Matsuo M, Tucker SJ, Komano T, Amachi T, Ueda K. Biochim Biophys Acta. 1998 Aug 14; 1373(1): 131-6. (9733949)
	Effect of modulators on the ATPase activity and vanadate nucleotide trapping of human P-glycoprotein. Shepard RL, Winter MA, Hsaio SC, Pearce HL, Beck WT, Dantzig AH. Biochem Pharmacol. 1998 Sep 15; 56(6): 719-27. (9751076)
	Substitution of alanine for serine 250 in the murine fatty acid transport protein inhibits long chain fatty acid transport. Stuhlsatz-Krouper et al., (1998). J. Biol. Chem. 273:28642-28650.  (9786857)
	The vesicle transport protein vps33p is an ATP-binding protein that localizes to the cytosol in an energy-dependent manner. Gerhardt et. al., (1998). J. Biol. Chem. 273:15818-15829. (9624182)
	Abnormal properties of creatine kinase in Alzheimer's disease brain: correlation of reduced enzyme activity and active site photolabeling with aberrant cytosol-membrane partitioning. David et. al., (1998). Brain Res. Mol. Brain Res. 54:276-287. (9555058)
	Mutations in either nucleotide-binding site of P-glycoprotein (Mdr3) prevent vanadate trapping of nucleotide at both site. Urbatsch et. al., (1998). Biochemistry 37:4592-4602. (9521779)
	Analysis of stress in the active site of myosin accompanied by conformational changes in transient state intermediate complexes using photoaffinity labeling and 19F-NMR spectroscopy. Maruta et. al., (1998). Eur. J. Biochem. 252:520-529. (9546669)
	Anti-cancer drugs and glutathione stimulate vanadate-induced trapping of nucleotide in multidrug resistance-associated protein (MRP). Taguchi Y, Yoshida A, Takada Y, Komano T, Ueda K. FEBS Lett 1997 Jan 13;401(1):11-4. (9003796)
	Inhibition of P-glycoprotein ATPase activity by procedures involving trapping of nucleotide in catalytic sites. Sankaran et. al., (1997). Arch. Biochem. Biophys. 341:160-169. (9143365)
	A comparison of changes in nucleotide-protein interactions in the striatal, hippocampus and paramedian cortex after cerebral ischemia and reperfusion: correlations to regional vulnerability. Sankaran et. al., (1997). Brain Res. Mol. Brain Res. 47:237-250.  (9221922)
	Functional modulation of ATPase of P-glycoprotein by C219, a monoclonal antibody against P-glycoprotein. Kokubu et. al., (1997). Biochem. Biophys. Res. Commun. 230:398-401. (9016791)
	Identification of adenine binding domain peptides of the NADP+ active site within porcine heart NADP(+)-dependent isocitrate dehydrogenase. Sankaran et. al., (1996). Biochemistry 35:13501-13510. (8885829)
	Localisation of an ATP-binding site on adenylyl cyclase type I after chemical and enzymatic fragmentation. Droste et. al., (1996). FEBS Lett. 391:209-214. (8706918)
	Determination of the nucleotide binding site within Clostridium symbiosum pyruvate phosphate dikinase by photoaffinity labeling, site-directed mutagenesis, and structural analysis. McGuire et. al., (1996). Biochemistry 35:8544-8552. (8679615)
	Recombinant N-terminal nucleotide-binding domain from mouse P-glycoprotein. Overexpression, purification, and role of cysteine 430. Dayan et. al., (1996). J. Biol. Chem. 271:11652-11658. (8662620)
	Identification of adenine binding domain peptides of the ADP regulatory site within glutamate dehydrogenase. Shoemaker and Haley (1996). Bioconjug. Chem. 7:302-310. (8816952)
	Kinetic and mutational dissection of the tow ATPase activities of terminase, the DNA packaging enzyme of bacteriophage Chi. Hwang et. al., (1996). Biochemistry 35:2796-2803. (8611586)
	Assembly, intracellular localization, and nucleotide binding properties of the human peptide transporters TAP1 and TAP2 expressed by recombinant vaccinia viruses. Russ et. al., (1995). J. Biol. Chem. 270:21312-21318. (7673167)
	P-glycoprotein is stably inhibited by vanadate-induced trapping of nucleotide at a single catalytic site. Urbatsch et. al., (1995). J. Biol. Chem. 270:19383-19390. (7642618)
	GroES and the chaperonin-assisted protein folding cycle: GroES has no affinity for nucleotides. Todd et. al., (1995). FEBS Lett. 359:123-125. (7867782)
	Photoaffinity labeling of creatine kinase with 2-azido- and 8-azidoadenosine triphosphate: identification of two peptides from the ATP-binding domain. Olcott et. al., (1994). Biochemistry 33:11935-11941. (7918412)
	Regulation of cytochrome c oxidase by interaction of ATP at two binding sites, one on subunit VIa. Taanman et. al., (1994). Biochemistry 33:11833-11841. (7918401)
	Effects of ATP on ligand recognition of platelet fibrinogen receptor on GPIIb-IIIa. Gawaz et al., (1994). Am. J. Physiol. 267:H1098-1106. (8092274)
	Characterization of KpsT, the ATP-binding component of the ABC-transporter involved with the export of capsular polysialic acid in Escherichia coli K1. Pavelka et. al., (1994). J. Biol. Chem. 269:20149-20158. (8051103)
	Nucleotide binding to the hydrophilic C-terminal domain of the transporter associated with antigen processing (TAP). Muller et. al., (1994). J. Biol. Chem. 269:14032-14037. (8188683)
	Photolabeling of mitochondrial F1-H+ATPase by 2-azido[3H]ADP entrapped as fluorometal complexes into the catalytic sites of the enzyme. Garin et. al., (1994). Biochemistry 33:3772-3777. (8142378)
	Characterization of the structural requirements for assembly and nucleotide binding of an ATP-binding cassette transporter. The maltose transport system of Escherichia coli. Panagiotidis et. al., (1993). J. Biol. Chem. 268:23685-23696. (8226895)
	Specific binding of ATP to extracellular sites on Torpedo acetylcholine receptor. Carlson and Raftery (1993). Biochemistry 32:7329-7333. (8393340)
	Interaction of nucleotides with membrane-associated cystic fibrosis transmembrane conductance regulator. Travis et. al., (1993). J. Biol. Chem. 268:15336-15339. (7687995)
	Photoaffinity labeling of skeletal myosin with 2-azidoadenosine triphosphate. Grammer et. al., (1993). Biochemistry 32:5725-5732. (8504091)
	Identification of amino acid residues photolabeled with 8-azidoadenosine 5'-triphosphate in the catalytic site of sarcoplasmic reticulum Ca-ATPase. Lacapere et. al., (1993). Biochemistry 32:3414-3421. (8384881)
	Combined application of site-directed mutagenesis, 2-azido-ATP labeling, and lin-benzo-ATP binding to study the noncatalytic sites of Escherichia coli F1-ATPase. Weber et. al., (1993). J. Biol. Chem. 268:6241-6247. (8454597)
	Identification of peptides from the adenine binding domains of ATP and AMP in adenylate kinase: isolation of photoaffinity-labeled peptides by metal chelate chromatography. Salvucci ME, Chavan AJ, Haley BE. Biochemistry (1992) May 12;31(18):4479-4487. (1581304)
	Labeling of two different regions of the nucleotide binding site of the uncoupling protein from brown adipose tissue mitochondria with two ATP analogs. Mayinger and Klingenberg (1992). Biochemistry 31:10536-10543. (1420170)
	Photoaffinity labeling of integrin alpha IIb beta 3 (glycoprotein IIb-IIIa) on intact platelets with 8-azido-[gamma-32P]ATP. Mayinger and Gawaz (1992). Biochim. Biophys. Acta 1137:77-81. (1390904)
	Detection of glutamine synthetase in the cerebrospinal fluid of Alzheimer diseased patients: a potential diagnostic biochemical marker. Gunnerson and Haley (1992). Proc. Natl. Acad. Sci. USA 89:11949-11953. (1361232)
	Photoaffinity labeling of dog pancreas microsomes with 8-azido-ATP inhibits association of nascent preprolactin with the signal sequence receptor complex. Zimmermann et al., (1991). FEBS Lett. 286:95-99. (1864386)
	A microsomal protein is involved in ATP-dependent transport of presecretory proteins into mammalian microsomes. Klappa et al., (1991). EMBO J. 10:2795-2803. (1833183)
	An ATP-binding membrane protein is required for protein translocation across th endoplasmic reticulum membrane. Zimmerman and Walter (1991). Cell Regul. 2:851-859. (1801920)
	Photoaffinity labeling of rotavirus VP1 with 8-azido-ATP: identification of the viral RNA polymerase. Valenzuela et. al., (1991). J. Virol. 65:3964-3967. (1645806)
	Heat shock induces a decrease in incorporation of 8-azidoadenosine 5'-triphosphate into a 42 kilodalton protein in Drosophila salivary glands. Rooney et. al., (1990). Biochim. Biophys. Acta 1034:102-106. (2109636)
	Photoaffinity labeling of ATP and NAD+ binding sites on recombinant human interleukin 2. Campbell et. al., (1990). Proc. Natl. Acad. Sci. USA 87:1243-1246. (2105502)
	Photoaffinity labeling of terminal deoxynucleotidyl transferase. 2. Identification of peptides in the nucleotide binding domain. Evans et. al., (1989). Biochemistry 28:713-720. (2713339)
	The ADP/ATP carrier from yeast (AAC-2) is uniquely suited for the assignment of the binding center by photoaffinity labeling. Mayinger et al., (1989). FEBS Lett. 244:421-426. (2537764)
	Photoaffinity labeling of DNA-dependent RNA polymerase from Escherichia coli with 8-azidoadenosine 5'-triophosphate. Woody et. al., (1984). Biochemistry 23:2843-2848. (6380575)
	Use of nucleotide photoaffinity probes to study hormone action. Khatoon et. a., (1983). Biol. Reprod. 28:61-73. (6299415)
	Development and utilization of 8-azidopurine nucleotide photoaffinity probes. Haley (1983). Fed. Proc. 42:2831-2836. (6307756)
	Tautomerism of 2-azidoadenine nucleotides. Efffects on enzyme kinetics and photoaffinity labeling . Czarnecki (1984). Biochim. Biophys. Acta 800:41-51. (6331519)
	The C2 catalytic domain of adenylyl cyclase contains the second metal ion (Mn2+) binding site. Mitterauer T, Hohenegger M, Tang WJ, Nanoff C, Freissmuth M. Biochemistry 1998 Nov 17;37(46):16183-91 (9819210)
	Characterization of microtubule-associated protein 1-associated protein kinases from rat brain. Fujii T, Watanabe M, Nakamura A. Neurochem Int 1996 May-Jun;28(5-6):535-44. (8792334)
	Characterization of the pp70 protein phosphorylation in the extract of rice young panicle. Cheng CM, Chow CK, Hu NT, Kuo TT. Biochem Biophys Res Commun 1991 Mar 15;175(2):467-72. (2018495)
	8-Azido-ATP (alpha 32P) binding to rod outer segment proteins. Shuster TA, Nagy AK, Farber DB. Exp Eye Res 1988 Apr;46(4):475-84. (3133234)
	Protein kinase activity associated with the purified rat hepatic glucocorticoid receptor. Miller-Diener A, Schmidt TJ, Litwack G. Proc Natl Acad Sci U S A 1985 Jun;82(12):4003-7. (3858857)
	Identification of a protein kinase as an intrinsic component of rat liver coated vesicles. Campbell C, Squicciarini J, Shia M, Pilch PF, Fine RE. Biochemistry 1984 Sep 11;23(19):4420-6. (6148963)
	The vesicle transport protein vps33p is an ATP-binding protein that localizes to the cytosol in an energy-dependent manner. Gerhardt et. al., (1998). J. Biol. Chem. 273:15818-15829. (9624182)
	Abnormal properties of creatine kinase in Alzheimer's disease brain: correlation of reduced enzyme activity and active site photolabeling with aberrant cytosol-membrane partitioning. David et. al., (1998). Brain Res. Mol. Brain Res. 54:276-287. (9555058)
	Mutations in either nucleotide-binding site of P-glycoprotein (Mdr3) prevent vanadate trapping of nucleotide at both site. Urbatsch et. al., (1998). Biochemistry 37:4592-4602. (9521779)
	Analysis of stress in the active site of myosin accompanied by conformational changes in transient state intermediate complexes using photoaffinity labeling and 19F-NMR spectroscopy. Maruta et. al., (1998). Eur. J. Biochem. 252:520-529. (9546669)
	Inhibition of P-glycoprotein ATPase activity by procedures involving trapping of nucleotide in catalytic sites. Sankaran et. al., (1997). Arch. Biochem. Biophys. 341:160-169. (9143365)
	A comparison of changes in nucleotide-protein interactions in the striatal, hippocampus and paramedian cortex after cerebral ischemia and reperfusion: correlations to regional vulnerability. Sankaran et. al., (1997). Brain Res. Mol. Brain Res. 47:237-250. (9221922)
	Functional modulation of ATPase of P-glycoprotein by C219, a monoclonal antibody against P-glycoprotein. Kokubu et. al., (1997). Biochem. Biophys. Res. Commun. 230:398-401. (9016791)
	Identification of adenine binding domain peptides of the NADP+ active site within porcine heart NADP(+)-dependent isocitrate dehydrogenase. Sankaran et. al., (1996). Biochemistry 35:13501-13510. (8885829)
	Localisation of an ATP-binding site on adenylyl cyclase type I after chemical and enzymatic fragmentation. Droste et. al., (1996). FEBS Lett. 391:209-214. (8706918)
	Determination of the nucleotide binding site within Clostridium symbiosum pyruvate phosphate dikinase by photoaffinity labeling, site-directed mutagenesis, and structural analysis. McGuire et. al., (1996). Biochemistry 35:8544-8552. (8679615)
	Recombinant N-terminal nucleotide-binding domain from mouse P-glycoprotein. Overexpression, purification, and role of cysteine 430. Dayan et. al., (1996). J. Biol. Chem. 271:11652-11658. (8662620)
	Identification of adenine binding domain peptides of the ADP regulatory site within glutamate dehydrogenase. Shoemaker and Haley (1996). Bioconjug. Chem. 7:302-310.(8816952)
	Kinetic and mutational dissection of the tow ATPase activities of terminase, the DNA packaging enzyme of bacteriophage Chi. Hwang et. al., (1996). Biochemistry 35:2796-2803. (8611586)
	Assembly, intracellular localization, and nucleotide binding properties of the human peptide transporters TAP1 and TAP2 expressed by recombinant vaccinia viruses. Russ et. al., (1995). J. Biol. Chem. 270:21312-21318. (7673167)
	P-glycoprotein is stably inhibited by vanadate-induced trapping of nucleotide at a single catalytic site. Urbatsch et. al., (1995). J. Biol. Chem. 270:19383-19390. (7642618)
	GroES and the chaperonin-assisted protein folding cycle: GroES has no affinity for nucleotides. Todd et. al., (1995). FEBS Lett. 359:123-125. (7867782)
	Photoaffinity labeling of creatine kinase with 2-azido- and 8-azidoadenosine triphosphate: identification of two peptides from the ATP-binding domain. Olcott et. al., (1994). Biochemistry 33:11935-11941. (7918412)
	Regulation of cytochrome c oxidase by interaction of ATP at two binding sites, one on subunit VIa. Taanman et. al., (1994). Biochemistry 33:11833-11841. (7918401)
	Characterization of KpsT, the ATP-binding component of the ABC-transporter involved with the export of capsular polysialic acid in Escherichia coli K1. Pavelka et. al., (1994). J. Biol. Chem. 269:20149-20158. (8051103)
	Nucleotide binding to the hydrophilic C-terminal domain of the transporter associated with antigen processing (TAP). Muller et. al., (1994). J. Biol. Chem. 269:14032-14037. (8188683)
	Photolabeling of mitochondrial F1-H+ATPase by 2-azido[3H]ADP entrapped as fluorometal complexes into the catalytic sites of the enzyme. Garin et. al., (1994). Biochemistry 33:3772-3777. (8142378)
	Characterization of the structural requirements for assembly and nucleotide binding of an ATP-binding cassette transporter. The maltose transport system of Escherichia coli. Panagiotidis et. al., (1993). J. Biol. Chem. 268:23685-23696. (8226895)
	Specific binding of ATP to extracellular sites on Torpedo acetylcholine receptor. Carlson and Raftery (1993). Biochemistry 32:7329-7333. (8393340)
	Interaction of nucleotides with membrane-associated cystic fibrosis transmembrane conductance regulator. Travis et. al., (1993). J. Biol. Chem. 268:15336-15339. (7687995)
	Photoaffinity labeling of skeletal myosin with 2-azidoadenosine triphosphate. Grammer et. al., (1993). Biochemistry 32:5725-5732. (8504091)
	Identification of amino acid residues photolabeled with 8-azidoadenosine 5'-triphosphate in the catalytic site of sarcoplasmic reticulum Ca-ATPase. Lacapere et. al., (1993). Biochemistry 32:3414-3421. (8384881)
	Combined application of site-directed mutagenesis, 2-azido-ATP labeling, and lin-benzo-ATP binding to study the noncatalytic sites of Escherichia coli F1-ATPase. Weber et. al., (1993). J. Biol. Chem. 268:6241-6247. (8454597)
	Detection of glutamine synthetase in the cerebrospinal fluid of Alzheimer diseased patients: a potential diagnostic biochemical marker. Gunnerson and Haley (1992). Proc. Natl. Acad. Sci. USA 89:11949-11953. (1361232)
	An ATP-binding membrane protein is required for protein translocation across th endoplasmic reticulum membrane. Zimmerman and Walter (1991). Cell Regul. 2:851-859. (1801920)
	Photoaffinity labeling of rotavirus VP1 with 8-azido-ATP: identification of the viral RNA polymerase. Valenzuela et. al., (1991). J. Virol. 65:3964-3967. (1645806)
	Heat shock induces a decrease in incorporation of 8-azidoadenosine 5'-triphosphate into a 42 kilodalton protein in Drosophila salivary glands. Rooney et. al., (1990). Biochim. Biophys. Acta 1034:102-106. (2109636)
	Photoaffinity labeling of ATP and NAD+ binding sites on recombinant human interleukin 2. Campbell et. al., (1990). Proc. Natl. Acad. Sci. USA 87:1243-1246. (2105502)
	Photoaffinity labeling of terminal deoxynucleotidyl transferase. 2. Identification of peptides in the nucleotide binding domain. Evans et. al., (1989). Biochemistry 28:713-720. (2713339)
	Photoaffinity labeling of DNA-dependent RNA polymerase from Escherichia coli with 8-azidoadenosine 5'-triophosphate. Woody et. al., (1984). Biochemistry 23:2843-2848. (6380575)
	Use of nucleotide photoaffinity probes to study hormone action. Khatoon et. a., (1983). Biol. Reprod. 28:61-73. (6299415)
	Development and utilization of 8-azidopurine nucleotide photoaffinity probes. Haley (1983). Fed. Proc. 42:2831-2836. (6307756)
	Tautomerism of 2-azidoadenine nucleotides. Efffects on enzyme kinetics and photoaffinity labeling . Czarnecki (1984). Biochim. Biophys. Acta 800:41-51.(6331519)

B.    Studies Employing 8N₃cAMP Photoaffinity Analogs

	Cyclic amp-dependent protein kinase isoenzymes in human myeloid leukemia (hl60) and breast tumor (mcf-7) cells. Taimi M, Breitman TR, Takahashi N. Arch Biochem Biophys 2001 Aug. 1;392(1):137-44. (11469804)
	Cyclic adenosine 3':5'-monophosphate-dependent protein kinase on the external surface of LS-174T human colon carcinoma cells. Kondrashin A, Nesterova M, Cho-Chung YS. Biochemistry 1999 Jan 5;38(1):172-9. (9890895)
	Mitosis-specific phosphorylation and subcellular redistribution of the RIIalpha regulatory subunit of cAMP-dependent protein kinase. Keryer G, Yassenko M, Labbe JC, Castro A, Lohmann SM, Evain-Brion D, Tasken K. J Biol Chem 1998 Dec 18;273(51):34594-602. (9852131)
	Characterization of PKA isoforms and kinase-dependent activation of chloride secretion in T84 cells. Singh AK, Tasken K, Walker W, Frizzell RA, Watkins SC, Bridges RJ, Bradbury NA. Am J Physiol 1998 Aug;275(2 Pt 1):C562-70. (9688611)
	Effects of [D-Ala1] peptide T-NH2 and HIV envelope glycoprotein gp120 on cyclic AMP dependent protein kinases in normal and psoriatic human fibroblasts. Liapi C, Takahashi N, Raynaud F, Evain-Brion D, Anderson WB. J Invest Dermatol 1998 Apr;110(4):332-7. (9540970)
	Isolation and characterisation of cAMP-dependent protein kinase from Candida albicans. Purification of the regulatory and catalytic subunits. Zelada A, Passeron S, Lopes Gomes S, Cantore ML. Eur J Biochem 1998 Mar 1;252(2):245-52. (9523695)
	Oxidative modulation of cyclic AMP-dependent protein kinase in human fibroblasts: possible role in psoriasis. Raynaud F, Evain-Brion D, Gerbaud P, Marciano D, Gorin I, Liapi C, Anderson WB. Free Radic Biol Med 1997;22(4):623-32. (9013125)
	Cyclic AMP-dependent protein kinase (cAK) in human B cells: co-localization of type I cAK (RI alpha 2 C2) with the antigen receptor during anti-immunoglobulin-induced B cell activation. Levy FO, Rasmussen AM, Tasken K, Skalhegg BS, Huitfeldt HS, Funderud S, Smeland EB, Hansson V. Eur J Immunol 1996 Jun;26(6):1290-6. (8647207)
	Retinoylation of the type II cAMP-binding regulatory subunit of cAMP-dependent protein kinase is increased in psoriatic human fibroblasts. Tournier S, Raynaud F, Gerbaud P, Lohmann SM, Anderson WB, Evain-Brion D. J Cell Physiol 1996 May;167(2):196-203. (8613459)
	Secretagogue-induced proteolysis of cAMP-dependent protein kinase in intact rat alveolar epithelial type II cells. Zimmerman UJ, Wang M, Nelson JB, Ekwunife FS, Liu L. Biochim Biophys Acta 1996 Apr 24;1311(2):117-23. (8630329)
	Type I A-kinase is activated by platelet-derived growth factor in mesangial cells. Throckmorton DC, Dickinson M, Dransfield DT. Biochem Biophys Res Commun 1996 Mar 27;220(3):692-6. (8607827)
	Characterization of protein kinase and phosphatase systems in chick ciliary ganglion. Lengyel I, N. Neuroscience 1996 Jan;70(2):577-88. (8848161)
	Cyclic 3'-5'-adenosine monophosphate binds to annexin I and regulates calcium-dependent membrane aggregation and ion channel activity. Cohen BE, Lee G, Arispe N, Pollard HB. FEBS Lett 1995 Dec 27;377(3):444-50. (8549773)
	Distribution of A-kinase anchoring proteins in parietal cells. Dransfield DT, Bradford AJ, Goldenring JR. Biochim Biophys Acta 1995 Nov 30;1269(3):215-20. (7495873)
	Characterization of a cAMP-binding protein from the bivalve mollusc Mytilus galloprovincialis. Cao J, Ramos-Martinez JI, Villamarin JA. Eur J Biochem 1995 Sep 1;232(2):664-70. (7556221)
	Post-translational abnormality of the type II cyclic AMP-dependent protein kinase in psoriasis: modulation by retinoic acid. Tournier S, Gerbaud P, Anderson WB, Lohmann SM, Evain-Brion D, Raynaud F. J Cell Biochem 1995 Apr;57(4):647-54. (7615649)
	Molecular interactions of 3',5'-cyclic purine analogues with the binding site of retinal rod ion channels. Scott SP, Tanaka JC. Biochemistry 1995 Feb 21;34(7):2338-47. (7532007)
	Association of the regulatory subunit of a type II cAMP-dependent protein kinase and its binding proteins with the fibrous sheath of rat sperm flagellum. Macleod J, Mei X, Erlichman J, Orr GA. Eur J Biochem 1994 Oct 1;225(1):107-14. (7925427)
	Cyclic AMP-dependent protein kinase in rat mammary tissue: expression of catalytic and regulatory subunits throughout pregnancy and lactation. Gardner RA, Travers MT, Barber MC, Miller WR, Clegg RA. Biochem J 1994 Aug 1;301 ( Pt 3):807-12. (8053905)
	Characterization of recombinant RI beta and evaluation of the presence of RI beta protein in rat brain and testicular extracts. DeManno DA, Jackiw V, Brooks E, Hunzicker-Dunn M. Biochim Biophys Acta 1994 Jul 21;1222(3):501-10. (8038221)
	Novel isozymes of cAMP-dependent protein kinase exist in human cells due to formation of RI alpha-RI beta heterodimeric complexes. Tasken K, Skalhegg BS, Solberg R, Andersson KB, Taylor SS, Lea T, Blomhoff HK, Jahnsen T, Hansson V. J Biol Chem 1993 Oct 5;268(28):21276-83. (8407966)
	Activation of an S6 kinase from human placenta by autophosphorylation. Dennis PB, Masaracchia RA. J Biol Chem 1993 Sep 15;268(26):19833-41. (8366121)
	Rapid effect of treatment of psoriatic erythrocytes with the synthetic retinoid acitretin to increase 8-azido cyclic AMP binding to the RI regulatory subunit. Raynaud F, Gerbaud P, Bouloc A, Gorin I, Anderson WB, Evain-Brion D. J Invest Dermatol 1993 Jan;100(1):77-81. (8380830)
	Cyclic AMP-dependent protein kinase in human embryonic palate mesenchymal cells. Greene RM, Lloyd MR, Pisano MM. In Vitro Cell Dev Biol 1992 Nov-Dec;28A(11-12):755-62. (1282915)
	Regulation of cyclic adenosine 3',5'-monophosphate-dependent protein kinase activity and regulatory subunit RII beta content by basic fibroblast growth factor (bFGF) during granulosa cell differentiation: possible implication of protein kinase C in bFGF action. Oury F, Faucher C, Rives I, Bensaid M, Bouche G, Darbon JM. Biol Reprod 1992 Aug;47(2):202-12. (1327204)
	Identification, purification, and characterization of subunits of cAMP-dependent protein kinase in human testis. Reverse mobilities of human RII alpha and RII beta on sodium dodecyl sulfate-polyacrylamide gel electrophoresis compared with rat and bovine RIIs. Skalhegg BS, Landmark B, Foss KB, Lohmann SM, Hansson V, Lea T, Jahnsen T. J Biol Chem 1992 Mar 15;267(8):5374-9. (1544918)
	Retinoylation of the cAMP-binding regulatory subunits of type I and type II cAMP-dependent protein kinases in HL60 cells. Takahashi N, Liapi C, Anderson WB, Breitman TR. Arch Biochem Biophys 1991 Nov 1;290(2):293-302. (1656875)
	Bcy1, the regulatory subunit of cAMP-dependent protein kinase in yeast, is differentially modified in response to the physiological status of the cell. Werner-Washburne M, Brown D, Braun E. J Biol Chem 1991 Oct 15;266(29):19704-9. (1655793)
	cAMP-binding proteins in epithelial cells cultured from human sweat glands. Pon DJ, Wong M, Riordan JR, Schimmer BP. Am J Physiol 1990 Jun;258(6 Pt 1):C1036-43. (2163195)
	Ontogenetic analysis of embryonic palatal type I and type II cAMP-dependent protein kinase isozymes. Linask KK, Greene RM. Cell Differ Dev 1989 Dec;28(3):189-202. (2620260)
	Cyclic AMP-dependent protein kinase in canine pancreatic rough endoplasmic reticulum. Nigam SK, Blobel G. J Biol Chem 1989 Oct 5;264(28):16927-32. (2550466)
	Multiple cAMP-binding proteins in Aplysia tissues. Palazzolo M, Katz F, Kennedy TE, Schwartz JH. J Neurobiol 1989 Dec;20(8):746-61. (2584964)
	Cyclic AMP-dependent protein kinase in canine pancreatic rough endoplasmic reticulum. Nigam SK, Blobel G. J Biol Chem 1989 Oct 5;264(28):16927-32. (2550466)
	Protein kinase A, cytosolic calcium, and phosphate uptake in human proximal renal cells. Middleton JP, Dunham CB, Onorato JJ, Sens DA, Dennis VW. Am J Physiol 1989 Oct;257(4 Pt 2):F631-8. (2478035)
	Altered function of protein kinase C and cyclic adenosine monophosphate-dependent protein kinase in a cell line derived from a mouse lung papillary tumor. Nicks KM, Droms KA, Fossli T, Smith GJ, Malkinson AM. Cancer Res 1989 Sep 15;49(18):5191-8. (2548715)
	cAMP-dependent phosphorylation of soluble and crude microtubule fractions of rat cerebral cortex after prolonged desmethylimipramine treatment. Perez J, Tinelli D, Brunello N, Racagni G. Eur J Pharmacol 1989 Aug 15;172(3):305-16. (2550266)
	Evidence that cyclic adenosine 3',5'-monophosphate-dependent protein kinase activation causes pig ovarian granulosa cell differentiation, including increases in two type II subclasses of this kinase. Beebe SJ, Segaloff DL, Burks D, Beasley-Leach A, Limbird LE, Corbin JD. Biol Reprod 1989 Aug;41(2):295-307. (2553142)
	Modulation of nuclear cyclic AMP-dependent protein kinase in dibutyryl cyclic AMP-treated rat H4IIE hepatoma cells. Squinto SP, Jungmann RA. Biochem J 1989 Jun 15;260(3):673-82. (2548485)
	A cAMP binding abnormality in psoriasis. Raynaud F, Gerbaud P, Enjolras O, Gorin I, Donnadieu M, Anderson WB, Evain-Brion D. Lancet 1989 May 27;1(8648):1153-6. (2566733)
	Biochemical and immunological characterization of the flagellar-associated regulatory subunit of a type II cyclic adenosine 5'-monophosphate-dependent protein kinase. Horowitz JA, Voulalas P, Wasco W, MacLeod J, Paupard MC, Orr GA. Arch Biochem Biophys 1989 May 1;270(2):411-8. (2650622)
	Cyclic AMP-dependent protein kinases of Paramecium. I. Chromatographic and physical properties of the enzymes from cilia. Mason PA, Nelson DL. Biochim Biophys Acta 1989 Jan 17;1010(1):108-15. (2909245)
	Subcellular compartmentalization of cAMP-dependent protein kinase regulatory subunits during palate ontogeny. Linask KK, Greene RM. Life Sci 1989;45(20):1863-8. (2557506)
	Thyrotropin but not epidermal growth factor down-regulates the isozyme I (PKa I) of cyclic AMP-dependent protein kinases in dog thyroid cells in primary cultures. Breton MF, Roger PP, Omri B, Dumont JE, Pavlovic-Hournac M. Mol Cell Endocrinol 1989 Jan;61(1):49-55. (2545480)
	Hormonal regulation of nuclear cyclic AMP-dependent protein kinase subunit levels in rat ovaries. Kwast-Welfeld J, Jungmann RA. J Biol Chem 1988 Oct 5;263(28):14343-50. (3139655)
	cAMP-binding proteins in medullary tubules from rat kidney: effect of ADH. Gapstur SM, Homma S, Dousa TP. Am J Physiol 1988 Aug;255(2 Pt 2):F292-300. (2841870)
	Effect of phorbol ester on cyclic adenosine 3':5'-monophosphate-dependent protein kinases in PYS teratocarcinoma-derived cells and counteraction with retinoic acid. Plet A, Gerbaud P, Anderson WB, Evain-Brion D. Cancer Res 1988 Jul 15;48(14):3993-7. (2838167)
	A nuclear cAMP binding protein in retinoic acid-treated HL-60 cells. Briggs RC, Casey SB. J Cell Physiol 1988 Jul;136(1):198-201. (2840443)
	An unusual protein kinase phosphorylates the chemotactic receptor of Dictyostelium discoideum. Meier K, Klein C. Proc Natl Acad Sci U S A 1988 Apr;85(7):2181-5. (2832847)
	Species specificity of antibodies to regulatory subunits of cyclic AMP-dependent protein kinases. Maddox AM, Steiner AL, Shenolikar S. Second Messengers Phosphoproteins 1988;12(2-3):83-94. (3244116)
	Type II cAMP-dependent protein kinase is associated with the rabbit kidney brush border membranes. Shenolikar S, Fischer K, Chang L, Weinman EJ. Second Messengers Phosphoproteins 1988;12(2-3):95-104. (2854161)
	Prostaglandin-E2-induced activation of adenosine 3'-5' cyclic monophosphate-dependent protein kinases of a murine macrophage-like cell line (P388D1). Yamamoto H, Suzuki T. J Immunol 1987 Nov 15;139(10):3416-21. (2824605)
	Retinoid treatment of human psoriatic fibroblasts induces an increase in cyclic AMP-dependent protein kinase activity. Raynaud F, Leduc C, Anderson WB, Evain-Brion D. J Invest Dermatol 1987 Jul;89(1):105-10. (3598199)
	The surface cyclic AMP receptor in Dictyostelium. Levels of ligand-induced phosphorylation, solubilization, identification of primary transcript, and developmental regulation of expression. Klein P, Vaughan R, Borleis J, Devreotes P. J Biol Chem 1987 Jan 5;262(1):358-64. (3025212)
	Purification of the surface cAMP receptor in Dictyostelium. Klein P, Knox B, Borleis J, Devreotes P. J Biol Chem 1987 Jan 5;262(1):352-7. (3025211)
	Species-dependent isoenzyme subtypes of membrane-bound cyclic AMP-dependent protein kinase in highly purified cardiac sarcolemma. Church JG, Derdemezi JB, Yuan S, Sen AK. Biochem J 1986 Sep 1;238(2):341-4. (3026349)
	Deficiency of cyclic AMP-dependent protein kinases in human psoriasis. Brion DE, Raynaud F, Plet A, Laurent P, Leduc B, Anderson W. Proc Natl Acad Sci U S A 1986 Jul;83(14):5272-6. (3014540)
	Insulin stimulates the generation of an adipocyte phosphoprotein that is isolated with a monoclonal antibody against the regulatory subunit of bovine heart cAMP-dependent protein kinase. Lawrence JC Jr, Hiken JF, Inkster M, Scott CW, Mumby MC. Proc Natl Acad Sci U S A 1986 Jun;83(11):3649-53. (2424009)
	Retinoic acid effect on cyclic AMP-dependent protein kinases in embryonal carcinoma cells: studies with differentiation-defective sublines. Plet A, Gerbaud P, Sherman MI, Anderson WB, Brion DE. J Cell Physiol 1986 May;127(2):341-7. (3700486)
	Cyclic AMP-dependent protein kinase isozymes of bovine epididymal spermatozoa: evidence against the existence of an ectokinase. Noland TD, Corbin JD, Garbers DL. Biol Reprod 1986 May;34(4):681-9. (3011134)
	Phosphorylation of three proteins in the plasma membrane of Y-1 adrenal cells by a membrane-bound adenosine 3',5'-monophosphate-dependent protein kinase. Widmaier EP, Osawa S, Hall PF. Endocrinology 1986 Feb;118(2):701-8. (3002763)
	Azido cAMP, [32P]8N3 cAMP: a probe to study epididymal sperm maturation. Atherton RW. Arch Androl 1986;17(2):101-3. (3030202)
	Vaginal fluid adenosine 3',5'-cyclic monophosphate (cAMP) in the rat: interaction with sperm cAMP-dependent protein kinase regulatory subunits. Atherton RW, Culver B, Seitz J, Khatoon S, Gern W. Arch Androl 1986;16(3):215-26. (3022659)
	Identification of the catalytic subunit of the ATP diphosphohydrolase by photoaffinity labeling of high-affinity ATP-binding sites of pancreatic zymogen granule membranes with 8-azido-[alpha-32P]ATP. LeBel D, Beattie M. Biochem Cell Biol 1986 Jan;64(1):13-20. (3008785)
	Covalent labelling of ligand binding sites of human placental S-adenosylhomocysteine hydrolase with 8-azido derivatives of adenosine and cyclic AMP. Aiyar VN, Hershfield MS. Biochem J 1985 Dec 15;232(3):643-50. (3004411)
	Regulation of the content and phosphorylation of RII by adenosine 3',5'-monophosphate, follicle-stimulating hormone, and estradiol in cultured granulosa cells. Ratoosh SL, Richards JS. Endocrinology 1985 Sep;117(3):917-27. (2990878)
	Activation of microsomal cAMP-dependent protein kinase isoenzyme I by ACTH1-24 in bovine adrenal cells. Deviller P, Vallier P, Saez JM. J Steroid Biochem 1985 Aug;23(2):133-6. (2993746)
	Regulation of protein kinase and its regulatory subunits during skeletal myogenesis. Rogers JE, Narindrasorasak S, Cates GA, Sanwal BD. J Biol Chem 1985 Jul 5;260(13):8002-7. (2989271)
	A comparative analysis of cAMP-dependent protein kinase regulatory subunits in sea urchin and rat spermatozoa. Khatoon S, Haley BE, Atherton RW. J Androl 1985 Jul-Aug;6(4):251-60. (2993217)
	Parietal cell protein kinases. Selective activation of type I cAMP-dependent protein kinase by histamine. Chew CS. J Biol Chem 1985 Jun 25;260(12):7540-50. (2987257)
	Phosphorylation of lens membranes with a cyclic AMP-dependent protein kinase purified from the bovine lens. Johnson KR, Panter SS, Johnson RG. Biochim Biophys Acta 1985 Mar 21;844(3):367-76. (2982431)
	Differentiation-associated increase of cAMP-dependent type II protein kinase in a murine preadipose cell line (ST 13). Sato M, Hiragun A, Mitsui H. Biochim Biophys Acta 1985 Mar 21;844(3):296-305. (2982429)
	A study of rat epididymal sperm adenosine 3',5'-monophosphate-dependent protein kinases: maturation differences and cellular location. Atherton RW, Khatoon S, Schoff PK, Haley BE. Biol Reprod 1985 Feb;32(1):155-71. (2982432)
	Assay of cyclic AMP-dependent protein kinase activity in canine myocardium: effect of coronary artery ligation on the cytosolic enzyme. Bartel S, Krause EG, Wollenberger A. Biomed Biochim Acta 1985;44(9):1303-13. (4084276)
	Changes in the activity and subcellular distribution of cyclic-AMP-dependent protein kinases with retinoic-acid-induced differentiation of embryonal carcinoma cells. Plet A, Gerbaud P, Anderson WB, Brion DE. Differentiation 1985;30(2):159-64. (3007248)
	Hormonal regulation of cyclic AMP-dependent protein kinase in cultured ovarian granulosa cells. Effects of follicle-stimulating hormone and gonadotropin-releasing hormone. Darbon JM, Knecht M, Ranta T, Dufau ML, Catt KJ. J Biol Chem 1984 Dec 10;259(23):14778-82. (6094574)
	Characterization of Leydig cell protein kinase. Further studies in hormone action. Winters CA, Dufau ML. FEBS Lett 1984 Dec 3;178(1):73-8. (6094257)
	Distribution and characterization of cAMP-dependent protein kinase isoenzymes in bovine adrenal cells. Deviller P, Vallier P, Bata J, Saez JM. Mol Cell Endocrinol 1984 Nov;38(1):21-30. (6097488)
	Specific photoaffinity labeling of the cAMP surface receptor in Dictyostelium discoideum. Theibert A, Klein P, Devreotes PN. J Biol Chem 1984 Oct 25;259(20):12318-21. (6092328)
	Microheterogeneity of type II cAMP-dependent protein kinase in various mammalian species and tissues. Robinson-Steiner AM, Beebe SJ, Rannels SR, Corbin JD. J Biol Chem 1984 Aug 25;259(16):10596-605. (6088506)
	Nucleolar accumulation of cyclic adenosine 3':5'-monophosphate receptor proteins during regression of MCF-7 human breast tumor. Kapoor CL, Grantham F, Cho-Chung YS. Cancer Res 1984 Aug;44(8):3554-60. (6331652)
	Purification of a novel isoform of the regulatory subunit of cAMP-dependent protein kinase from the bivalve mollusk Mytilus galloprovincialis. Rodriguez JL, Barcia R, Ramos-Martinez JI, Villamarin JA. Arch Biochem Biophys 1998 Nov 1;359(1):57-62. (9799560)
	Guanosine 3',5'-cyclic nucleotide binding proteins of bovine retina identified by photoaffinity labeling. Thompson DA, Khorana HG. Proc Natl Acad Sci U S A 1990 Mar;87(6):2201-5. (2156264)

C.    Studies Employing ATP-Azidoanilide and ATP-Benzophenone Photoaffinity Analogs

	Direct photoaffinity labeling of Kir6.2 by [gamma-(32)P]ATP-[gamma]4-azidoanilide. Tanabe K, Tucker SJ, Ashcroft FM, Proks P, Kioka N, Amachi T, Ueda K. Biochem Biophys Res Commun 2000 Jun 7;272(2):316-9. (10833411)
	Photobinding of [gamma-(32)P] ATP gamma-benzophenone to the surface of a polyurethane membrane in the preparation of a beta-particle-emitting balloon catheter. Kim SH, Tartaglino SG, Burpee S, Pendergrass JC, Jay M. J Biomed Mater Res 1999;48(5):669-74. (10490680)
	ATP nucleotidylation of creatine kinase. David SS, Haley BE. Biochemistry 1999 Jun 29;38(26):8492-500. (10387096)
	Benzophenone photoprobes for phosphoinositides, peptides and drugs. Prestwich et al., (1997). Photochem. Photobiol. 65:222-234. (9066302)
	Benzophenone photoprobes in biochemistry. Dorman and Prestwich. (1994). Biochemistry 33: 5661-5673. (8180191)
	Photoaffinity labeling of ribulose-1,5-bisphosphate carboxylase/oxygenase activase with ATP gamma-benzophenone. Identification of the ATP gamma-phosphate binding domain. Salvucci ME, Rajagopalan K, Sievert G, Haley BE, Watt DS. J Biol Chem 1993 Jul 5;268(19):14239-44. (8314787)
	Synthesis and application of bidentate photoaffinity cross-linking reagents. Rajagopalan et. al., (1993). J. Biol. Chem. 266:14230-14238. (8314786)
	Photolabeling of the 6 and 10 S conformations of gizzard myosin with 3'(2')-O-(4-benzoyl-ATP. Cole and Yount (1990). J. Biol. Chem. 265:22537-22542. (2266144)
	Characterization and photoaffinity labeling of the ATP binding site of the ryanodine receptor from skeletal muscle. Zarka A, Shoshan-Barmatz V. Eur J Biochem 1993 Apr 1;213(1):147-54. (8386621)
	Serine-324 of myosin's heavy chain is photoaffinity-labeled by 3'(2')-O-(4-benzoylbenzoyl)adenosine triphosphate. Mahmood R, Elzinga M, Yount RG. Biochemistry 1989 May 2;28(9):3989-95. (2502175)
	Photochemical probes of the active site of myosin. Irradiation of trapped 3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate labels the 50-kilodalton heavy chain tryptic peptide. Mahmood R, Yount RG.  Biol Chem 1984 Nov 10;259(21):12956-9. (6238030)
	Labeling the adenine nucleotide binding domain of the sarcoplasmic reticulum Ca,Mg-ATPase with photoaffinity analogs of ATP. Cable and Briggs. (1984). J. Biol. Chem. 259:3612-3615. (6142892)
	Exploring the adenine nucleotide binding sites on mitochondrial F1-ATPase with a new photoaffinity probe, 3'-O-(4-benzoyl adenosine 5'triphosphate. Williams and Coleman. (1982). J. Biol. Chem. 257:2834-2841. (6460764)
	Benzophenone-ATP: a photoaffinity label for the active site of ATPases. Williams N, Ackerman SH, Coleman PS. Methods Enzymol 1986;126:667-82. (2908476)
	Photoaffinity labelling of arginine kinase and creatine kinase with the g-P-substituted arylazido analogue of ATP. Vandest et al., (1980). Eur. J. Biochem. 104:433-442.
	The use of aryl azido ATP analogs as photoaffinity labels for myosin ATPase. Jeng and Guillory. (1975). J. Supramolecular Structure 3:448-468.

D.    Studies Employing 8N₃GTP and GTP-Azido Anilide Photoaffinity Analogs

	Functional characterization of the adrenoleukodystrophy protein (ALDP) and disease pathogenesis. Gartner J, Dehmel T, Klusmann A, Roerig P. Endocr Res 2002 Nov;28(4):741-8. (12530690)
	Age increases cardiac Galpha(i2) expression, resulting in enhanced coupling to G protein-coupled receptors. Kilts JD, Akazawa T, Richardson MD, Kwatra MM. J Biol Chem. 2002 Aug 23;277(34):31257-62. Epub 2002 Jun 13. (12065589)
	Purification and properties of Mycobacterial GDP-mannose pyrophosphorylase. Ning and Elbein. (1999). Arch. Biochem. Biophys. 362:339-345. (9989944)
	G protein G alpha q/11 and G alpha i1,2 are activated by pancreastatin receptors in rat liver: studies with GTP-gamma 35S and azido-GTP-alpha-32P. Santos-Alvarez J, Sanchez-Margalet V. J Cell Biochem 1999 Jun 15;73(4):469-77. (10733341)
	The beta3-adrenergic receptor activates mitogen-activated protein kinase in adipocytes through a Gi-dependent mechanism. Soeder KJ, Snedden SK, Cao W, Della Rocca GJ, Daniel KW, Luttrell LM, Collins S. J Biol Chem 1999 Apr 23;274(17):12017-22. (10207024)
	Receptor-mediated activation of G-proteins by kappa opioid agonists in frog (Rana esculenta) brain membranes. Rottman et al., (1998). Brain Res. Bull. 45:467-474. (9570716)
	Mercury vapor inhalation inhibits binding of GTP to tubulin in rat brain: similarity to a molecular lesion in Alzheimer diseased brain. Pendergrass et. al., (1997). Neurotoxicology 18:315-324.(9291481)
	Inhibition of brain tubulin-guanosine 5'-triphosphate interactions by mercury: similarity to observations in Alzheimer's diseased brain. Pendergrass and Haley (1997). Met. Ions Biol. Sys. 34:461-478.(9046580)
	Mutagenesis of segment 487Phe-Ser-Arg-Asp--Arg-Lys492 of sarcoplasmic reticulum Ca2+-ATPase produces pumps defective in ATP binding. McIntosh et. al., (1996). J. Biol. Chem. 271:25778-25789.(8824206)
	Identification of a peptide of the guanosine triphosphate binding site within brain glutamate dehydrogenase isoproteins using 8-azidoguanosine triphosphate. Cho et. al., (1996). Biochemistry 35:13907-13913.(8909287)
	Determination of the nucleotide binding site within Clostridium symbosium pyruvate phosphate dikinase by photoaffinity labeling, site-directed mutagenesis, and structural analysis. McGuire et. al., (1996). Biochemistry 35:8544-8552.(8679615)
	Activation of GTP formation and high-affinity GTP hydrolysis by mastoparan in various cell membranes. G-protein activation via nucleoside diphosphate kinase, a possible general mechanism of mastoparan action.  Klinker et. al., (1996). Biochem. Pharmacol. 51:217-223.(8573186)
	Tubulin stimulates adenyly cyclase activity in rat striatal membranes via transfer of guanine nucleotide to Gs protein. Hatta et. al., (1995). Brain Res. 704:23-30.(8750958)
	Participation of tubulin in the stimulatory regulation of adenylyl cyclase in rat cerebral cortex membranes. Hatta et. al., (1995). J. Neurochem. 64:1343-1350.(7861167)
	Evidence that the 50-kDa substate of brefeldin A-dependent ADP-ribosylation binds GTP and is modulated by the G-protein beta gamma subunit complex. Di Girolamo et. al., (1995). Proc. Natl. Acad. Sci. USA 92:7065-7069.(7624370)
	Guanosine triphosphate binding to beta-subunit of tubulin in Alzheimer's disease brain: role of microtubule-associated protein tau. Khatoon et. al., (1995). J. Neurochem. 64:777-787.(7830071)
	Photoaffinity labeling of influenza virus RNA polymerase PB1 subunit with 8-azido GTP. Asano et. al., (1995). J. Biochem. 117:677-682.(7629040)
	Alteration of tubulin-Gi protein interaction in rat cerebral cortex with aging. Hatta et. al., (1994). J. Neurochem. 63:1104-1110.(8051551)
	Alterations of receptor-G protein-adenylyl cyclase coupling in alcoholics. Saito et. al., (1994). Alcohol. Alcohol. Suppl. 2:211-215.(8974338)
	Reduced sensitivity to ethanol of Gs alpha and Gi/o alpha in the cerebral cortex of alcoholic patients. Ozawa et. al., (1994). Alcohol Alcohol. 29:93-97.(9063827)
	Effects of ethanol on the function of G proteins in rat cerebral cortex membranes. Hatta et. al., (1994). Alcohol Alcohol. 29:45-51.(9063818)
	2',3'-Dialdehyde GTP as an irreversible G protein antagonist. Disruption and reconstitution of G protein-mediated signal transduction in cells and cell membranes. Nanoff et. al., (1994). J. Biol. Chem. 269:31999-32007.(7989376)
	Alteration of tubulin-Gi protein interaction in rat cerebral cortex with aging. Hatta et. al., (1994). J. Neurochem. 63:1104-1110.(8051551)

	Age-related alterations on GTP binding proteins in postmortem human brain. Hashimoto et. al., (1994). Yakubutsu Seishin Kodo 14:93-104.(8042348)
	Function and amount o GTP binding proteins in postmortem human brain in dementia of Alzheimer's type.  Hashimoto et. al., (1994). Yakubutsu Seishin Kodo 14:105-109.(8042344)
	Identification of peptides within the base binding domains of the GTP- and ATP-specific binding sites of tubulin. Jayaram and Haley (1994). J. Biol. Chem. 269:3233-3242.(8106359)
	G proteins of the G12 family are activated via thromboxane A2 and thrombin receptors in human platelets. Offermans et. al., (1994). Proc. Natl. Acad. Sci. USA 91:504-508.(8290554)
	Synthesis and application of bidentate photoaffinity cross-linking reagents. Nucleotide photoaffinity probes with two photoactive groups.  Rajagopalan et. al., (1993). J. Biol. Chem. 268:14230-14238.(8314786)
	Identification of a guanine binding domain peptide of the GTP binding site of glutamate dehydrogenase: isolation with metal-chelate affinity chromatography. Shoemaker and Haley (1993). Biochemistry 32:1883-1890.(8439545)
	(D-Ala, D-Leu) enkephalin reduces the binding of GTP in hippocampal membranes. Aramaki et. al., (1993). Life Sci. 52:901-906.(8445984)
	HgEDTA complex inhibits GTP interactions with the E-site of brain beta-tubulin. Duhr et. al., (1993). Toxicol. Appl. Pharmacol. 122:273-280.(8212009)
	Alterations of guanine nucleotide-binding proteins in post-mortem human brain in alcoholics. Ozawa et. al., (1993). Brain Res. 620:174-179.(8402195)
	Effects of ethanol on GTP-binding protein function in human brain cortex. Ozawa et. al., (1993). Arukoru Kenkyuto Yakubutsu Iso 28:49-53.(8317966)
	Effects of chronic low-level lead exposure on mRNA expression, ADP-ribosylation and photoaffinity labeling with [alpha-32P]guanine triphosphate-gamma-azidoanilide of GTP-binding proteins in neurons isolated from the brain of neonatal and adult rats. Singh (1993). Biochem. Pharmacol. 45:1107-1114. (8461040)
	G protein binding and G protein activation by nucleotide transfer involve distinct domains on tubulin: regulation of signal transduction by cytoskeletal elements. Roychowdry et. al., (1993). Biochemistry 32:4955-4961.(8490031)
	Imbalance of the Gs and Gi/o function in post-mortem human brain of depressed patients. Ozawa et. al., (1993). J. Neural. Trans. Gen. Sect. 94:63-69.(8129882)
	Identification of the guanine binding domain peptide of the GTP-binding site of glucagon. Shoemaker et. al., (1992). Protein Sci. 1:884-891.(1304373)
	Classical conditioning-induced changes in low-molecular-weight GTP-binding proteins in rabbit hippocampus. Nelson et. al., (1991). J. Neurochem. 57:2065-2069.(1940916)
	The interaction of a kainate receptor from goldfish brain with a pertussis toxin-sensitve GTP-binding protein. Willard et. al., (1991). J. Biol. Chem. 266:10196-10200.(1674742)
	Chronic electroconvulsive treatment augments coupling of the GTP-binding protein Gs to the catalytic moiety of adenylyl cyclase in a manner similar to that seen with chronic antidepressant drugs. Qzawa and Rasenick (1991). J. Neurochem. 56:330-338.(1898967)

	Evidence for the simultaneous translocation of muscarinic acetylcholine receptor and G protein by carbachol. Ho et. al., (1991). Cell Signal 3:587-598.(1786207)
	Evidence for opioid receptor-mediated activation of the G-proteins, Go and Gi2, in membranes of neuroblastoma x glioma (NG108-15) hybrid cells. Offermanns et. al., (1991). J. Biol. Chem. 266:3365-3368.(1671672)
	Photoaffinity labeling of atrial natriuretic factor analog atriopeptin III with [gamma-32P]8N3GTP. Mann et. al., (1991). Pept. Res. 4:79-83.(1840030)
	A novel guanine nucleotide-binding protein coupled to the alpha 1-adrenergic receptor. I. Identification by photolabeling or membrane and ternary complex preparation. Im and Graham (1990). J. Biol. Chem. 265:18944-18951.(2172239)
	Agonist-sensitive binding of a photoreactive GTP analog to a G-protein alpha-subunit in membranes of HL-60 cells. Offermans et. al., (1990). FEBS Lett. 260:14-18.(2153575)
	Aberrant guanosine triphosphate-beta-tubulin interaction in Alzheimer's disease. Khatoon et. al., (1989). Ann. Neurol. 26:210-215.(2774507)
	Exchangeable GTP binding site of the beta-subunit of brain tubulin in Alzheimer's diseasse. Khatoon and Iqbal. (1989). Prog. Clin. Biol. Res. 317:801-807.(2690125)
	Coupling of the stimulatory GTP-binding protein Gs to rat synaptic membrane adenylate cyclase is enhanced subsequent to chronic antidepressant treatment. Ozawa and Rasenick (1989). Mol. Pharmacol. 36:803-808.(2511428)
	Modification of Gs-stimulated adenylate cyclase in brain membranes by low pH treatment: correlation with altered guanine nucleotide exchange. Rasenick and Childers (1989). J. Neurochem. 53:219-225.(2498464)
	Guanosine-5'-O-thiodiphosphate functions as a partial agonist for the receptor-independent stimulation of neural adenylate cyclase. Rasenick et. al., (1989). Brain Res. 488:105-113.(2743106)
	Decreased 8N3[gamma32P]GTP photolabeling of Gs alpha in tumorigenic lung eptheial cell lines: association with decreased hormone responsiveness and loss of contact-inhibited growth. Droms et. al., (1989). Exp. Cell Res. 182:330-339.(2542068)
	Formation of an intramolecular cystine disulfide during the reaction of 8-azidoguanosine 5'-triphosphate with cytosolic phosphoenolpyruvate carboxykinase (GTP) causes inactivation without photolabeling. Lewis et. al., (1989). Biochemistry 28:9248-9255.(2611226)
	Growth rate dependence of differential incorporation of a guanosine triphosphate photoaffinity probe into the alpha subunit of a guanine nucleotide binding protein, Gs, from metastic variants of B16 melanoma cells. Lange-Carter et. al., (1989). Cancer Res. 49:3173-3177.(2541898)
	Stucture of the alpha and beta heavy chains of the outer arm dynein from Chlamydomonas flagella. Nucleotide binding site. King et. al., (1989). J. Biol. Chem. 264:10210-10218.(2524490)
	Exchange of guanine nucleotides between tubulin and GTP-binding proteins that regulate adenylate cyclase: cytoskeletal modification of neuronal signal transduction. Rasenick and Wang (1988). J. Neurochem. 51:300-311.(3132535)
	In situ binding of a photo-affinity GTP analog to synaptic membrane G-proteins. Distribution of bound BTP analog reflects the status of adenylate cyclase. Gordon and Rasenick (1988). FEBS Lett. 235:201-206.(3136034)
	Identification and purification from bovine brain of a guanine-nucleotide-binding protein from distinct Gs, Gi, and Go. Waldo et. al., (1987). Biochem. J. 246:431-439.(3120696)
	Characterization of the guanosine-3'-diphosphate-5'-diphosphate binding site on E. coli RNA polymerase using a photoprobe, 8-azidoguanosine-3'-5'-bisphosphate. Owens et. al., (1987). Biochem. Biophys. Res. Commun. 142:964-971.(3548721)
	Use of nucleotide photoaffinity probes to study hormone action. Khatoon et. a., (1983). Biol. Reprod. 28:61-73.(6299415)
	Development and utilization of 8-azidopurine nucleotide photoaffinity probes. Haley (1983). Fed. Proc. 42:2831-2836.(6307756)
	Use of a GTP photoaffinity probe to resolve aspects of the mechanism of tubulin polymerization. Geahlen and Haley (1979). J. Biol. Chem. 254:11982-11987.(500687)
	Interactions of a photoaffinity analog of GTP with the proteins of microtubules. Geahlen and Haley (1977). Proc. Natl. Acad. Sci. USA 74:4375-4377.(270679)
	G protein G alpha q/11 and G alpha i1,2 are activated by pancreastatin receptors in rat liver: studies with GTP-gamma 35S and azido-GTP-alpha-32P. Santos-Alvarez J, Sanchez-Margalet V. J Cell Biochem 1999 Jun 15;73(4):469-77. (10733341)
	The beta3-adrenergic receptor activates mitogen-activated protein kinase in adipocytes through a Gi-dependent mechanism. Soeder KJ, Snedden SK, Cao W, Della Rocca GJ, Daniel KW, Luttrell LM, Collins S. J Biol Chem 1999 Apr 23;274(17):12017-22. (10207024)
	Growth rate dependence of differential incorporation of a guanosine triphosphate photoaffinity probe into the alpha subunit of a guanine nucleotide binding protein, Gs, from metastatic variants of B16 melanoma cells. Cancer Res 1989 Jun 15;49(12):3173-7. (2541898)
	Functional alterations of G-proteins in diabetic rat retina: a possible explanation for the early visual abnormalities in diabetes mellitus. Kowluru A, Kowluru RA, Yamazaki A. Diabetologia 1992 Jul;35(7):624-31. (1322850)
	Mercury vapor inhalation inhibits binding of GTP to tubulin in rat brain: similarity to a molecular lesion in Alzheimer diseased brain. Pendergrass et. al., (1997). Neurotoxicology 18:315-324.(9291481)
	Inhibition of brain tubulin-guanosine 5'-triphosphate interactions by mercury: similarity to observations in Alzheimer's diseased brain. Pendergrass and Haley (1997). Met. Ions Biol. Sys. 34:461-478.(9046580)
	Mutagenesis of segment 487Phe-Ser-Arg-Asp--Arg-Lys492 of sarcoplasmic reticulum Ca2+-ATPase produces pumps defective in ATP binding. McIntosh et. al., (1996). J. Biol. Chem. 271:25778-25789.(8824206)
	Identification of a peptide of the guanosine triphosphate binding site within brain glutamate dehydrogenase isoproteins using 8-azidoguanosine triphosphate. Cho et. al., (1996). Biochemistry 35:13907-13913.(8909287)
	Determination of the nucleotide binding site within Clostridium symbosium pyruvate phosphate dikinase by photoaffinity labeling, site-directed mutagenesis, and structural analysis. McGuire et. al., (1996). Biochemistry 35:8544-8552.(8679615)
	Activation of GTP formation and high-affinity GTP hydrolysis by mastoparan in various cell membranes. G-protein activation via nucleoside diphosphate kinase, a possible general mechanism of mastoparan action.  Klinker et. al., (1996). Biochem. Pharmacol. 51:217-223.(8573186)
	Tubulin stimulates adenyly cyclase activity in rat striatal membranes via transfer of guanine nucleotide to Gs protein. Hatta et. al., (1995). Brain Res. 704:23-30.(8750958)
	Participation of tubulin in the stimulatory regulation of adenylyl cyclase in rat cerebral cortex membranes. Hatta et. al., (1995). J. Neurochem. 64:1343-1350.(7861167)
	Evidence that the 50-kDa substate of brefeldin A-dependent ADP-ribosylation binds GTP and is modulated by the G-protein beta gamma subunit complex. Di Girolamo et. al., (1995). Proc. Natl. Acad. Sci. USA 92:7065-7069.(7624370)
	Guanosine triphosphate binding to beta-subunit of tubulin in Alzheimer's disease brain: role of microtubule-associated protein tau. Khatoon et. al., (1995). J. Neurochem. 64:777-787.(7830071)
	Photoaffinity labeling of influenza virus RNA polymerase PB1 subunit with 8-azido GTP. Asano et. al., (1995). J. Biochem. 117:677-682.(7629040)
	Alteration of tubulin-Gi protein interaction in rat cerebral cortex with aging. Hatta et. al., (1994). J. Neurochem. 63:1104-1110.(8051551)
	Alterations of receptor-G protein-adenylyl cyclase coupling in alcoholics. Saito et. al., (1994). Alcohol. Alcohol. Suppl. 2:211-215.(8974338)
	Reduced sensitivity to ethanol of Gs alpha and Gi/o alpha in the cerebral cortex of alcoholic patients. Ozawa et. al., (1994). Alcohol Alcohol. 29:93-97.(9063827)
	Effects of ethanol on the function of G proteins in rat cerebral cortex membranes. Hatta et. al., (1994). Alcohol Alcohol. 29:45-51.(9063818)
	2',3'-Dialdehyde GTP as an irreversible G protein antagonist. Disruption and reconstitution of G protein-mediated signal transduction in cells and cell membranes. Nanoff et. al., (1994). J. Biol. Chem. 269:31999-32007.(7989376)
	Alteration of tubulin-Gi protein interaction in rat cerebral cortex with aging. Hatta et. al., (1994). J. Neurochem. 63:1104-1110.(8051551)

	Age-related alterations on GTP binding proteins in postmortem human brain. Hashimoto et. al., (1994). Yakubutsu Seishin Kodo 14:93-104.(8042348)
	Function and amount o GTP binding proteins in postmortem human brain in dementia of Alzheimer's type.  Hashimoto et. al., (1994). Yakubutsu Seishin Kodo 14:105-109.(8042344)
	Identification of peptides within the base binding domains of the GTP- and ATP-specific binding sites of tubulin. Jayaram and Haley (1994). J. Biol. Chem. 269:3233-3242.(8106359)
	G proteins of the G12 family are activated via thromboxane A2 and thrombin receptors in human platelets. Offermans et. al., (1994). Proc. Natl. Acad. Sci. USA 91:504-508.(8290554)
	Synthesis and application of bidentate photoaffinity cross-linking reagents. Nucleotide photoaffinity probes with two photoactive groups.  Rajagopalan et. al., (1993). J. Biol. Chem. 268:14230-14238.(8314786)
	Identification of a guanine binding domain peptide of the GTP binding site of glutamate dehydrogenase: isolation with metal-chelate affinity chromatography. Shoemaker and Haley (1993). Biochemistry 32:1883-1890.(8439545)
	(D-Ala, D-Leu) enkephalin reduces the binding of GTP in hippocampal membranes. Aramaki et. al., (1993). Life Sci. 52:901-906.(8445984)
	HgEDTA complex inhibits GTP interactions with the E-site of brain beta-tubulin. Duhr et. al., (1993). Toxicol. Appl. Pharmacol. 122:273-280.(8212009)
	Alterations of guanine nucleotide-binding proteins in post-mortem human brain in alcoholics. Ozawa et. al., (1993). Brain Res. 620:174-179.(8402195)
	Effects of ethanol on GTP-binding protein function in human brain cortex. Ozawa et. al., (1993). Arukoru Kenkyuto Yakubutsu Iso 28:49-53.(8317966)
	Effects of chronic low-level lead exposure on mRNA expression, ADP-ribosylation and photoaffinity labeling with [alpha-32P]guanine triphosphate-gamma-azidoanilide of GTP-binding proteins in neurons isolated from the brain of neonatal and adult rats. Singh (1993). Biochem. Pharmacol. 45:1107-1114. (8461040)
	G protein binding and G protein activation by nucleotide transfer involve distinct domains on tubulin: regulation of signal transduction by cytoskeletal elements. Roychowdry et. al., (1993). Biochemistry 32:4955-4961.(8490031)
	Imbalance of the Gs and Gi/o function in post-mortem human brain of depressed patients. Ozawa et. al., (1993). J. Neural. Trans. Gen. Sect. 94:63-69.(8129882)
	Identification of the guanine binding domain peptide of the GTP-binding site of glucagon. Shoemaker et. al., (1992). Protein Sci. 1:884-891.(1304373)
	Classical conditioning-induced changes in low-molecular-weight GTP-binding proteins in rabbit hippocampus. Nelson et. al., (1991). J. Neurochem. 57:2065-2069.(1940916)
	The interaction of a kainate receptor from goldfish brain with a pertussis toxin-sensitve GTP-binding protein. Willard et. al., (1991). J. Biol. Chem. 266:10196-10200.(1674742)
	Chronic electroconvulsive treatment augments coupling of the GTP-binding protein Gs to the catalytic moiety of adenylyl cyclase in a manner similar to that seen with chronic antidepressant drugs. Qzawa and Rasenick (1991). J. Neurochem. 56:330-338.(1898967)
	Evidence for the simultaneous translocation of muscarinic acetylcholine receptor and G protein by carbachol. Ho et. al., (1991). Cell Signal 3:587-598.(1786207)
	Evidence for opioid receptor-mediated activation of the G-proteins, Go and Gi2, in membranes of neuroblastoma x glioma (NG108-15) hybrid cells. Offermanns et. al., (1991). J. Biol. Chem. 266:3365-3368.(1671672)
	Photoaffinity labeling of atrial natriuretic factor analog atriopeptin III with [gamma-32P]8N3GTP. Mann et. al., (1991). Pept. Res. 4:79-83.(1840030)
	A novel guanine nucleotide-binding protein coupled to the alpha 1-adrenergic receptor. I. Identification by photolabeling or membrane and ternary complex preparation. Im and Graham (1990). J. Biol. Chem. 265:18944-18951.(2172239)
	Agonist-sensitive binding of a photoreactive GTP analog to a G-protein alpha-subunit in membranes of HL-60 cells. Offermans et. al., (1990). FEBS Lett. 260:14-18.(2153575)
	Aberrant guanosine triphosphate-beta-tubulin interaction in Alzheimer's disease. Khatoon et. al., (1989). Ann. Neurol. 26:210-215.(2774507)
	Exchangeable GTP binding site of the beta-subunit of brain tubulin in Alzheimer's diseasse. Khatoon and Iqbal. (1989). Prog. Clin. Biol. Res. 317:801-807.(2690125)
	Coupling of the stimulatory GTP-binding protein Gs to rat synaptic membrane adenylate cyclase is enhanced subsequent to chronic antidepressant treatment. Ozawa and Rasenick (1989). Mol. Pharmacol. 36:803-808.(2511428)
	Modification of Gs-stimulated adenylate cyclase in brain membranes by low pH treatment: correlation with altered guanine nucleotide exchange. Rasenick and Childers (1989). J. Neurochem. 53:219-225.(2498464)
	Guanosine-5'-O-thiodiphosphate functions as a partial agonist for the receptor-independent stimulation of neural adenylate cyclase. Rasenick et. al., (1989). Brain Res. 488:105-113.(2743106)
	Decreased 8N3[gamma32P]GTP photolabeling of Gs alpha in tumorigenic lung eptheial cell lines: association with decreased hormone responsiveness and loss of contact-inhibited growth. Droms et. al., (1989). Exp. Cell Res. 182:330-339.(2542068)
	Formation of an intramolecular cystine disulfide during the reaction of 8-azidoguanosine 5'-triphosphate with cytosolic phosphoenolpyruvate carboxykinase (GTP) causes inactivation without photolabeling. Lewis et. al., (1989). Biochemistry 28:9248-9255.(2611226)
	Growth rate dependence of differential incorporation of a guanosine triphosphate photoaffinity probe into the alpha subunit of a guanine nucleotide binding protein, Gs, from metastic variants of B16 melanoma cells. Lange-Carter et. al., (1989). Cancer Res. 49:3173-3177.(2541898)
	Stucture of the alpha and beta heavy chains of the outer arm dynein from Chlamydomonas flagella. Nucleotide binding site. King et. al., (1989). J. Biol. Chem. 264:10210-10218.(2524490)
	Exchange of guanine nucleotides between tubulin and GTP-binding proteins that regulate adenylate cyclase: cytoskeletal modification of neuronal signal transduction. Rasenick and Wang (1988). J. Neurochem. 51:300-311.(3132535)
	In situ binding of a photo-affinity GTP analog to synaptic membrane G-proteins. Distribution of bound BTP analog reflects the status of adenylate cyclase. Gordon and Rasenick (1988). FEBS Lett. 235:201-206.(3136034)
	Identification and purification from bovine brain of a guanine-nucleotide-binding protein from distinct Gs, Gi, and Go. Waldo et. al., (1987). Biochem. J. 246:431-439.(3120696)
	Characterization of the guanosine-3'-diphosphate-5'-diphosphate binding site on E. coli RNA polymerase using a photoprobe, 8-azidoguanosine-3'-5'-bisphosphate. Owens et. al., (1987). Biochem. Biophys. Res. Commun. 142:964-971.(3548721)
	Use of nucleotide photoaffinity probes to study hormone action. Khatoon et. a., (1983). Biol. Reprod. 28:61-73.(6299415)
	Development and utilization of 8-azidopurine nucleotide photoaffinity probes. Haley (1983). Fed. Proc. 42:2831-2836.(6307756)
	Use of a GTP photoaffinity probe to resolve aspects of the mechanism of tubulin polymerization. Geahlen and Haley (1979). J. Biol. Chem. 254:11982-11987.(500687)
	Interactions of a photoaffinity analog of GTP with the proteins of microtubules. Geahlen and Haley (1977). Proc. Natl. Acad. Sci. USA 74:4375-4377.(270679)

E.    Studies Employing 5N₃UTP and 5N₃UDP Analogs

	Identification of two uridine binding domain peptides of the UDP-glucose-binding site of rabbit muscle glycogenin. Carrizo and Curtino. (1998). Biochem. Biophys. Res. Commun. 253:786-789. (9918805)
	Synthesis of 5-azido-UDP-N-acetylhexosamine photoaffinity analogs and radiolabeled UDP-N-acetylhexosamines. Sunthankar et. al., (1998). Anal. Biochem. 258:195-201.(9570829)
	Photoaffinity labeling studies of the human recombinant UDP-glucuronosyltransferase, UGT1*6, with 5-azido-UDP-glucuronic acid. Battaglia et. al., (1997). Drug Metab. Dispos. 25:406-411.(9107538)
	Characterization of human liver microsomal UDP-glycosyltransferases using photoaffinity analogs. Little et. al., (1995). J. Pharmacol. Exp. Ther. 273:1551-1559.(7791131)
	Characterization of UDP-glucuronic acid transport in rat liver microsomal vesicles with photoaffinity analogs. Radominska et. al., (1994). Biochim. Biophys. Acta 1195:63-70.(7918567)
	Photidentification of mannosyltransferases of dolichol cycle in the mammary gland. Purification and characterization of GDP-Man:Man beta 1-->4GlcNAc beta 1-->4GlcNAc-P-P-dolichol mannosyltransferase. Mudgapalli et. al., (1994). J. Biol. Chem. 269:11327-11336.(7512562)
	Application of 5-azido-UDP-glucose and 5-azido-UDP-glucuronic acid photoaffinity probes for the determination of the active site orientation of microsomal UDP-glucosyltransferases and UDP-glucouronosyltransferases. Drake et. al., (1992). J. Biol. Chem. 267:11360-11365.(1534561)
	Identification of the Escherichia coli 30S ribosomal subunit protein neighboring mRNA durin initiation of translation. Dontsova et. al., (1992). Biochime 74:363-371.(1379079)
	Purification and photoaffinity labeling of sucrose phosphate synthase from spinach leaves. Salvucci et. al., (1990). Arch. Biochem. Biophys. 281:212-218.(2144103)
	Identification of the uridine 5'-diphosphoglucose (UDP-Glc) binding subunit of cellulose synthase in Acetobacter xylinum using the photoaffinity probe 5-azido-UDP-Glc. Lin et. al., (1990). J. Biol. Chem. 265:4782-4784.(2138620)
	Identification of the UDP-glucose-binding polypeptide of callose sythase from Beta vulgaris L. by photoaffinity labeling with 5-azido-UDP-glucose. Frost et. al., (1990). J. Biol. Chem. 265:162-2167.(2137125)
	Characterization of a photoaffinity analog of UTP, 5-azido-UTP for analysis of the substrate binding site on E. coli RNA polymerase. Woody et. al., (1988). Biochem. Biophys. Res. Commun. 150:917-924.(2449209)
	Synthesis of 5-azido-UDP-N-acetylhexosamine photoaffinity analogs and radiolabeled UDP-N-acetylhexosamines. Sunthankar et. al., (1998). Anal. Biochem. 258:195-201.(9570829)
	Photoaffinity labeling studies of the human recombinant UDP-glucuronosyltransferase, UGT1*6, with 5-azido-UDP-glucuronic acid. Battaglia et. al., (1997). Drug Metab. Dispos. 25:406-411.(9107538)
	Characterization of human liver microsomal UDP-glycosyltransferases using photoaffinity analogs. Little et. al., (1995). J. Pharmacol. Exp. Ther. 273:1551-1559.(7791131)
	Characterization of UDP-glucuronic acid transport in rat liver microsomal vesicles with photoaffinity analogs. Radominska et. al., (1994). Biochim. Biophys. Acta 1195:63-70.(7918567)
	Photidentification of mannosyltransferases of dolichol cycle in the mammary gland. Purification and characterization of GDP-Man:Man beta 1-->4GlcNAc beta 1-->4GlcNAc-P-P-dolichol mannosyltransferase. Mudgapalli et. al., (1994). J. Biol. Chem. 269:11327-11336.(7512562)
	Application of 5-azido-UDP-glucose and 5-azido-UDP-glucuronic acid photoaffinity probes for the determination of the active site orientation of microsomal UDP-glucosyltransferases and UDP-glucouronosyltransferases. Drake et. al., (1992). J. Biol. Chem. 267:11360-11365.(1534561)
	Identification of the Escherichia coli 30S ribosomal subunit protein neighboring mRNA durin initiation of translation. Dontsova et. al., (1992). Biochime 74:363-371.(1379079)
	Purification and photoaffinity labeling of sucrose phosphate synthase from spinach leaves. Salvucci et. al., (1990). Arch. Biochem. Biophys. 281:212-218.(2144103)
	Identification of the uridine 5'-diphosphoglucose (UDP-Glc) binding subunit of cellulose synthase in Acetobacter xylinum using the photoaffinity probe 5-azido-UDP-Glc. Lin et. al., (1990). J. Biol. Chem. 265:4782-4784.(2138620)
	Identification of the UDP-glucose-binding polypeptide of callose sythase from Beta vulgaris L. by photoaffinity labeling with 5-azido-UDP-glucose. Frost et. al., (1990). J. Biol. Chem. 265:162-2167.(2137125)
	Characterization of a photoaffinity analog of UTP, 5-azido-UTP for analysis of the substrate binding site on E. coli RNA polymerase. Woody et. al., (1988). Biochem. Biophys. Res. Commun. 150:917-924.(2449209)

F.    Studies Employing Biotinylated Nucleotide Photoaffinity Analogs

	Novel unconventional binding site in the variable region of immunoglobulins. Rajagopalan et. al., (1996). Proc. Natl. Acad. Sci. USA 93:6019-6024.(8650212)
	Site specific photobiotinylation of immunoglobulins, fragments and light chain dimers. Pavlinkova et. al., (1997). J. Immunol. Methods 201:77-88.(9032411)