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	8-Bromoguanosine 5'-triphosphate (8BrGTP)
	8-Bromoguanosine 5'-diphosphate (8BrGDP)
	8-Bromoguanosine 5'-monophosphate (8BrGMP -cm)
	8-Bromoguanosine 3',5'-cyclic monophosphate (8BrcGMP)

8-Bromoguanosine 5'-triphosphate (8BrGTP)

Molecular Formula: C₁₀H₁₁N₅O₁₄P₃Br

Molecular Weight: 598.04 for the free acid

Description: Triethylammonium salt solution in absolute methanol

UV Characteristics:

Absorbance maximum (l_max)= 262 nm at pH 7.0

Molar extinction coefficient (e ) = 15100

Assay: >95% by TLC

Storage: Store at -20^oC, protect from UV light including sunlight.   Compound is not affected by ordinary room lighting including fluorescent light.

8-Bromoguanosine 5'-diphosphate (8BrGDP)

Molecular Formula: C₁₀H₁₁N₅O₁₁P₂Br

Molecular Weight: 519.07 for the free acid

Description: Triethylammonium salt solution in absolute methanol

UV Characteristics:

Absorbance maximum (l_max)= 262 nm at pH 7.0

Molar extinction coefficient (e ) = 15100

Assay: >95% by TLC

Storage: Store at -20^oC, protect from UV light including sunlight.   Compound is not affected by ordinary room lighting including fluorescent light.

8-Bromoguanosine 5'-monophosphate (8BrGMP)

Molecular Formula: C₁₀H₁₁N₅O₈PBr

Molecular Weight: 440.1 for the free acid

Description: Triethylammonium salt solution in absolute methanol

UV Characteristics:

Absorbance maximum (l_max)= 262 nm at pH 7.0

Molar extinction coefficient (e ) = 15100

Assay: >95% by TLC

Storage: Store at -20^oC, protect from UV light including sunlight.   Compound is not affected by ordinary room lighting including fluorescent light.

8-Bromoguanosine 3',5'-cyclic monophosphate (8BrcGMP)

Molecular Formula: C₁₀H₁₀N₅O₇PBr

Molecular Weight: 423.1 for the free acid

Description: Triethylammonium salt solution in absolute methanol

UV Characteristics:

Absorbance maximum (l_max)= 262 nm at pH 7.0

Molar extinction coefficient (e ) = 15100

Assay: >95% by TLC

Storage: Store at -20^oC, protect from UV light including sunlight.   Compound is not affected by ordinary room lighting including fluorescent light.

8-Bromoguanosine-3',5'-cyclic monophosphate, triethylammonium salt, Storage: -20°C, A cell permeable cGMP analog which is more resistant to phosphodiesterases than cGMP and which preferentially activates cGMP-dependent protein kinase^1-3. It inhibits thrombin stimulated arachidonic acid release in human platelets⁴.

¹ R.B. Meyer and J.P. Miller Life Sci. 1974 14 1019

² S.G. Francis et al. Mol. Pharmacol. 1988 34 506

³ K.D. Schultz et al. Naunyn-Schmiedeberg's Pharmacol. 1979 306 1

⁴ D.C. Sane et al. Biochem. Biophys. Res. Commun. 1989 165 708